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Wiki Wiki Summary
Anti-competitive practices Anti-competitive practices are business or government practices that prevent or reduce competition in a market. Antitrust laws differ among state and federal laws to ensure businesses do not engage in competitive practices that harm other, usually smaller, businesses or consumers.
Profitability index Profitability index (PI), also known as profit investment ratio (PIR) and value investment ratio (VIR), is the ratio of payoff to investment of a proposed project. It is a useful tool for ranking projects because it allows you to quantify the amount of value created per unit of investment.
Transfusion-related acute lung injury Transfusion-related acute lung injury (TRALI) is the serious complication of transfusion of blood products that is characterized by the rapid onset of excess fluid in the lungs. It can cause dangerous drops in the supply of oxygen to body tissues.
Product design Product design as a verb is to create a new product to be sold by a business to its customers. A very broad coefficient and effective generation and development of ideas through a process that leads to new products.
Grasshopper Manufacture Grasshopper Manufacture Inc. (株式会社グラスホッパー・マニファクチュア, Kabushiki Gaisha Gurasuhoppā Manifakuchua) is a Japanese video game developer founded on March 30, 1998 by Goichi Suda.
Permission (film) Permission is a 2017 American romantic comedy-drama film written and directed by Brian Crano. The film stars Rebecca Hall as a woman on the brink of a marriage proposal from her boyfriend (Dan Stevens), but is impeded by the suggestion of her brother (David Joseph Craig) and his life partner (Morgan Spector) to "test date" other men before she ultimately settles down.
Jim Crow laws Jim Crow laws were state and local laws enforcing racial segregation in the Southern United States. Other areas of the United States were affected by formal and informal policies of segregation as well, but many states outside the South had adopted laws, beginning in the late 19th century, banning discrimination in public accommodations and voting.
Regulation (European Union) A regulation is a legal act of the European Union that becomes immediately enforceable as law in all member states simultaneously. Regulations can be distinguished from directives which, at least in principle, need to be transposed into national law.
Local average treatment effect The local average treatment effect (LATE), also known as the complier average causal effect (CACE), was first introduced into the econometrics literature by Guido W. Imbens and Joshua D. Angrist in 1994. It is the treatment effect for the subset of the sample that takes the treatment if and only if they were assigned to the treatment, otherwise known as the compliers.
Transfer of Undertakings (Protection of Employment) Regulations 2006 The Transfer of Undertakings (Protection of Employment) Regulations 2006 (SI 2006/246) known colloquially as TUPE and pronounced TU-pee, are the United Kingdom's implementation of the European Union Transfer of Undertakings Directive. It is an important part of UK labour law, protecting employees whose business is being transferred to another business.
List of telecommunications regulatory bodies This article is a list of the legal regulatory bodies that govern telecommunications systems in different countries. \nThis list contains bodies ensuring effective regulatory role in a territory which is not necessarily a state, but is listed as "territory" or "economy" in the statistics of international institutions, in particular the International Telecommunication Union (ITU).
List of states and territories of the United States The United States of America is a federal republic consisting of 50 states, a federal district (Washington, D.C., the capital city of the United States), five major territories, and various minor islands. The 48 contiguous states and Washington, D.C., are in North America between Canada and Mexico.
Democratic Party (United States) The Democratic Party is one of the two major contemporary political parties in the United States. It was founded in 1828 by supporters of Andrew Jackson, making it the world's oldest active political party.
Recognition of prior learning Recognition of prior learning (RPL), prior learning assessment (PLA), or prior learning assessment and recognition (PLAR), describes a process used by regulatory bodies, adult learning centres, career development practitioners, military organizations, human resources professionals, employers, training institutions, colleges and universities around the world to evaluate skills and knowledge acquired outside the classroom for the purpose of recognizing competence against a given set of standards, competencies, or learning outcomes. RPL is practiced in many countries for a variety of purposes, for example an individual's standing in a profession, trades qualifications, academic achievement, recruitment, performance management, career and succession planning.Methods of assessing prior learning are varied and include: evaluation of prior experience gained through volunteer work, previous paid or unpaid employment, or observation of actual workplace behavior.
Monitoring (medicine) In medicine, monitoring is the observation of a disease, condition or one or several medical parameters over time.\nIt can be performed by continuously measuring certain parameters by using a medical monitor (for example, by continuously measuring vital signs by a bedside monitor), and/or by repeatedly performing medical tests (such as blood glucose monitoring with a glucose meter in people with diabetes mellitus).
Electronic tagging Electronic tagging is a form of surveillance that uses an electronic device affixed to a person.\nIn some jurisdictions, an electronic tag fitted above the ankle is used for people as part of their bail or probation conditions.
MKUltra Project MKUltra (or MK-Ultra) was the code name of an illegal human experimentation program designed and undertaken by the U.S. Central Intelligence Agency (CIA). The experiments were intended to develop procedures and identify drugs such as LSD that could be used in interrogations to weaken individuals and force confessions through brainwashing and psychological torture.
Recycling Recycling is the process of converting waste materials into new materials and objects. The recovery of energy from waste materials is often included in this concept.
Tesla Roadster (first generation) The Tesla Roadster is a battery electric vehicle (BEV) sports car, based on the Lotus Elise chassis, that was produced by the electric car firm Tesla Motors (now Tesla, Inc.) in California from 2008 to 2012. The Roadster was the first highway legal serial production all-electric car to use lithium-ion battery cells and the first production all-electric car to travel more than 320 kilometres (200 mi) per charge.
Low-dropout regulator A low-dropout regulator (LDO regulator) is a DC linear voltage regulator that can regulate the output voltage even when the supply voltage is very close to the output voltage.The advantages of an LDO regulator over other DC-to-DC voltage regulators include the absence of switching noise (as no switching takes place), smaller device size (as neither large inductors nor transformers are needed), and greater design simplicity (usually consists of a reference, an amplifier, and a pass element). The disadvantage is that, unlike switching regulators, linear DC regulators must dissipate power, and thus heat, across the regulation device in order to regulate the output voltage.
Emerging technologies Emerging technologies are technologies whose development, practical applications, or both are still largely unrealized, such that they are figuratively emerging into prominence from a background of nonexistence or obscurity. These technologies are generally new but also include older technologies.
Gettysburg Address The Gettysburg Address is a speech that U.S. President Abraham Lincoln delivered during the American Civil War at the dedication of the Soldiers' National Cemetery in Gettysburg, Pennsylvania, on the afternoon of November 19, 1863, four and a half months after the Union armies defeated those of the Confederacy at the Battle of Gettysburg. It is one of the best-known speeches in American history.Lincoln's carefully crafted address, not even that day's primary speech, came to be seen as one of the greatest and most influential statements of American national purpose.
Blackburn Buccaneer The Blackburn Buccaneer is a British carrier-capable attack aircraft designed in the 1950s for the Royal Navy (RN). Designed and initially produced by Blackburn Aircraft at Brough, it was later officially known as the Hawker Siddeley Buccaneer when Blackburn became a part of the Hawker Siddeley Group, but this name is rarely used.
Cournot competition Cournot competition is an economic model used to describe an industry structure in which companies compete on the amount of output they will produce, which they decide on independently of each other and at the same time. It is named after Antoine Augustin Cournot (1801–1877) who was inspired by observing competition in a spring water duopoly.
Proprietary firmware Proprietary firmware is any firmware on which is not free (libre). Examples of proprietary works include ones upon which the author has placed restrictions on use, private modification, copying, or republishing.
Schedule A schedule or a timetable, as a basic time-management tool, consists of a list of times at which possible tasks, events, or actions are intended to take place, or of a sequence of events in the chronological order in which such things are intended to take place. The process of creating a schedule — deciding how to order these tasks and how to commit resources between the variety of possible tasks — is called scheduling, and a person responsible for making a particular schedule may be called a scheduler.
Adverse possession Adverse possession, sometimes colloquially described as "squatter's rights", is a legal principle in the Anglo-American common law under which a person who does not have legal title to a piece of property—usually land (real property)—may acquire legal ownership based on continuous possession or occupation of the property without the permission (licence) of its legal owner. The possession by a person is not adverse if they are in possession as a tenant or licensee of the legal owner.
Profitability analysis In cost accounting, profitability analysis is an analysis of the profitability of an organisation's output. Output of an organisation can be grouped into products, customers, locations, channels and/or transactions.
Customer profitability Customer Profitability Analysis (in short CPA) is a management accounting and a credit underwriting method, allowing businesses and lenders to determine the profitability of each customer or segments of customers, by attributing profits and costs to each customer separately. CPA can be applied at the individual customer level (more time consuming, but providing a better understanding of business situation) or at the level of customer aggregates / groups (e.g.
List of circulating currencies There are 180 currencies recognized as legal tender in United Nations (UN) member states, UN observer states, partially recognized or unrecognized states, and their dependencies. However, excluding the pegged (fixed exchange rate) currencies, there are only 130 currencies that are independent or pegged to a currency basket.
List of age restrictions This article gives an outline of age restrictions.
Natural environment The natural environment or natural world encompasses all living and non-living things occurring naturally, meaning in this case not artificial. The term is most often applied to the Earth or some parts of Earth.
Parkinson's disease Parkinson's disease (PD), or simply Parkinson's, is a long-term degenerative disorder of the central nervous system that mainly affects the motor system. The symptoms usually emerge slowly, and as the disease worsens, non-motor symptoms become more common.
National Institute for Communicable Diseases The National Institute for Communicable Diseases (NICD) is the national public health institute of South Africa, providing reference to microbiology, virology, epidemiology, surveillance and public health research to support the government's response to communicable disease threats.The NICD serves as a resource of knowledge and expertise of communicable diseases to the South African Government, Southern African Development Community countries and the African continent. The institution assists in the planning of policies and programmes to support and respond to communicable diseases.The main goal of the NICD is to be the national organ for South Africa for public health surveillance of communicable disease.
Surgical instrument A surgical instrument is a tool or device for performing specific actions or carrying out desired effects during a surgery or operation, such as modifying biological tissue, or to provide access for viewing it. Over time, many different kinds of surgical instruments and tools have been invented.
Risk Factors
You should refer to the explanation of the qualifications and limitations on forward-looking statements beginning on page 47
Our inability to successfully expand the business, through internal research and development, marketing partnerships and acquisitions, could have a material adverse effect on our business
Promising partnerships and acquisitions may not be completed for reasons such as competition among prospective partners or buyers, our inability to reach satisfactory terms, or the need for regulatory approvals
Any acquisition that we complete may be dilutive to earnings and require that we invest significant resources
We may not be able to integrate any acquired businesses successfully into our existing business, make such businesses profitable, or realize anticipated market growth or cost savings
If we are unable to successfully keep pace with technological advances in the medical field and the standards for transfusion medicine, our business, financial condition and results of operation could be adversely affected
The success of our products will depend upon our ability to anticipate and meet the needs of the medical field, particularly those who practice transfusion medicine
Additionally, we must be able to manufacture the products in a cost effective manner, with high quality and obtain permission to market and sell the products from various regulatory authorities
As a medical device manufacturer we are subject to a number of existing laws and regulations, non-compliance with those laws or regulations could adversely affect our financial condition and results of operations
The manufacture, distribution and marketing of our products are subject to regulation by the FDA and other non-United States regulatory bodies
Some regulatory authorities outside the United States may have a bias in favor of locally produced goods that could delay or prevent our achieving regulatory approval to market our products in such geographies
We must obtain specific regulatory clearance prior to selling any new product or service, and our operations are also subject to continuous review and monitoring by the FDA and other regulatory authorities
The process of obtaining approval to market and distribute our products is costly and time-consuming
Export of US technology or goods manufactured in the United States to some jurisdictions requires special US export authorization that may be influenced by factors, including political dynamics, outside our control
Changes in privacy regulations and other developments in human subjectsclinical trials could make it more difficult and more expensive to conduct clinical trials necessary for product approval
Regulations about the use of certain materials in the manufacture of health care products could also require us to identify alternate material(s), which may be at higher costs
The number of eligible blood donors is influenced by government regulations (including travel restrictions, health history, etc) and other economic and sociological factors
Changes in donation related regulations could have significant immediate effects on the population of eligible donors
We are subject to various actions by government authorities that regulate medical devices including: product recalls, orders to cease manufacturing or distribution activities, and other sanctions or penalties
Compliance with these regulations is costly and additional regulation could adversely affect our results of operations
Our customers are also subject to these regulations
Our customers’ compliance with applicable regulations could also affect our results of operations
17 ______________________________________________________________________ Many of our competitors have significantly greater financial and other resources
Their greater financial resources may allow them to more rapidly develop new technologies, and more quickly address changes in customer requirements
Although no one company competes with us across our full line of products, we face competition in each of our product lines
Our ability to remain competitive depends on a combination of factors, including those within our control (reputation, regulatory approvals, patents, unpatented proprietary know-how in several technological areas, product quality, safety, cost effectiveness and continued rigorous documentation of clinical performance) as well as factors outside of our control (regulatory standards, medical standards and the practice of medicine)
Also, sales of unauthorized copies of our products by local competitors in China could affect the demand and price paid for our products
As a multinational corporation, we are exposed to fluctuations in currency exchange rates, which could adversely affect our cash flows and results of operations
International revenues account for a substantial portion of our revenues, and we intend to continue expanding our presence in international markets
In 2006, our international revenues accounted for approximately 61prca of our total revenues
The exposure to fluctuations in currency exchange rates takes different forms
Reported revenues for sales made in foreign currencies by our international businesses, when translated into US dollars for financial reporting purposes, fluctuate due to exchange rate movement
Fluctuations in exchange rates could adversely affect our profitability in US dollars of products and services sold by us into international markets, where payment for our products and services is made in local currencies
We are subject to the risks of international economic and political conditions
Our international operations are subject to risks which are inherent in conducting business overseas and under foreign laws, regulations and customs
These risks include possible nationalization, expropriation, importation limitations, violations of US or local laws, pricing restrictions, and other restrictive governmental actions
Any significant changes in the competitive, political, legal, regulatory, reimbursement or economic environment where we conduct international operations may have a material impact on our business, financial condition or results of operations
We are subject to the risks associated with communicable diseases
A significant outbreak of a disease could reduce the demand for our products and affect our ability to provide our customers with products and services
An eligible donor’s willingness to donate is affected by concerns about their personal health and safety
Concerns about communicable diseases (such as HIV, SARS or pandemic bird flu) could reduce the number of donors, and accordingly reduce the demand for our products for a period of time
A significant outbreak of a disease could also affect our employees’ ability to work, which could limit our ability to produce product and service our customers