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Integration testing Integration testing (sometimes called integration and testing, abbreviated I&T) is the phase in software testing in which individual software modules are combined and tested as a group. Integration testing is conducted to evaluate the compliance of a system or component with specified functional requirements.
Integrator An integrator in measurement and control applications is an element whose output signal is the time integral of its input signal. It accumulates the input quantity over a defined time to produce a representative output.
Contour integration In the mathematical field of complex analysis, contour integration is a method of evaluating certain integrals along paths in the complex plane.Contour integration is closely related to the calculus of residues, a method of complex analysis.\nOne use for contour integrals is the evaluation of integrals along the real line that are not readily found by using only real variable methods.Contour integration methods include:\n\ndirect integration of a complex-valued function along a curve in the complex plane (a contour);\napplication of the Cauchy integral formula; and\napplication of the residue theorem.One method can be used, or a combination of these methods, or various limiting processes, for the purpose of finding these integrals or sums.
Continuous integration In software engineering, continuous integration (CI) is the practice of merging all developers' working copies to a shared mainline several times a day. Grady Booch first proposed the term CI in his 1991 method, although he did not advocate integrating several times a day.
European integration European integration is the process of industrial, economic, political, legal, social and cultural integration of states wholly or partially in Europe or nearby. European integration has primarily come about through the European Union and its policies.
Lebesgue integration In mathematics, the integral of a non-negative function of a single variable can be regarded, in the simplest case, as the area between the graph of that function and the x-axis. The Lebesgue integral, named after French mathematician Henri Lebesgue, extends the integral to a larger class of functions.
Arithmetic Arithmetic (from Ancient Greek ἀριθμός (arithmós) 'number', and τική [τέχνη] (tikḗ [tékhnē]) 'art, craft') is an elementary part of mathematics that consists of the study of the properties of the traditional operations on numbers—addition, subtraction, multiplication, division, exponentiation, and extraction of roots. In the 19th century, Italian mathematician Giuseppe Peano formalized arithmetic with his Peano axioms, which are highly important to the field of mathematical logic today.
Operation Mincemeat Operation Mincemeat was a successful British deception operation of the Second World War to disguise the 1943 Allied invasion of Sicily. Two members of British intelligence obtained the body of Glyndwr Michael, a tramp who died from eating rat poison, dressed him as an officer of the Royal Marines and placed personal items on him identifying him as the fictitious Captain (Acting Major) William Martin.
Bitwise operation In computer programming, a bitwise operation operates on a bit string, a bit array or a binary numeral (considered as a bit string) at the level of its individual bits. It is a fast and simple action, basic to the higher-level arithmetic operations and directly supported by the processor.
Special Activities Center The Special Activities Center (SAC) is a division of the Central Intelligence Agency responsible for covert operations and paramilitary operations. The unit was named Special Activities Division (SAD) prior to 2015.
Operations research Operations research (British English: operational research), often shortened to the initialism OR, is a discipline that deals with the development and application of advanced analytical methods to improve decision-making. It is sometimes considered to be a subfield of mathematical sciences.
Operation (mathematics) In mathematics, an operation is a function which takes zero or more input values (called operands) to a well-defined output value. The number of operands (also known as arguments) is the arity of the operation.
Surgery Surgery is a medical or dental specialty that uses operative manual and instrumental techniques on a person to investigate or treat a pathological condition such as a disease or injury, to help improve bodily function, appearance, or to repair unwanted ruptured areas.\nThe act of performing surgery may be called a surgical procedure, operation, or simply "surgery".
Arrested Development Arrested Development is an American television sitcom created by Mitchell Hurwitz, which originally aired on Fox for three seasons from 2003 to 2006, followed by a two-season revival on Netflix from 2013 to 2019. The show follows the Bluths, a formerly wealthy dysfunctional family.
Sustainable development Sustainable development is an organizing principle for meeting human development goals while also sustaining the ability of natural systems to provide the natural resources and ecosystem services on which the economy and society depend. The desired result is a state of society where living conditions and resources are used to continue to meet human needs without undermining the integrity and stability of the natural system.
Development/For! Development/For! (Latvian: Attīstībai/Par!, AP!) is a liberal political alliance in Latvia.
Research and development Research and development (R&D or R+D), known in Europe as research and technological development (RTD), is the set of innovative activities undertaken by corporations or governments in developing new services or products, and improving existing ones. Research and development constitutes the first stage of development of a potential new service or the production process.
Software development Software development is the process of conceiving, specifying, designing, programming, documenting, testing, and bug fixing involved in creating and maintaining applications, frameworks, or other software components. Software development involves writing and maintaining the source code, but in a broader sense, it includes all processes from the conception of the desired software through to the final manifestation of the software, typically in a planned and structured process.
Personal development Personal development or self improvement consists of activities that develop a person's capabilities and potential, build human capital, facilitate employability, and enhance quality of life and the realization of dreams and aspirations. Personal development may take place over the course of an individual's entire lifespan and is not limited to one stage of a person's life.
Prenatal development Prenatal development (from Latin natalis 'relating to birth') includes the development of the embryo and of the foetus during a viviparous animal's gestation. Prenatal development starts with fertilization, in the germinal stage of embryonic development, and continues in fetal development until birth.
Life Insurance Corporation Life Insurance Corporation of India (LIC) is an Indian statutory insurance and investment corporation headquartered in the city of Mumbai, India. It is under the ownership of Government of India.
Defence mechanism In psychoanalytic theory, a defence mechanism (American English: defense mechanism), is an unconscious psychological operation that functions to protect a person from anxiety-producing thoughts and feelings related to internal conflicts and outer stressors.Defence mechanisms may result in healthy or unhealthy consequences depending on the circumstances and frequency with which the mechanism is used. Defence mechanisms (German: Abwehrmechanismen) are psychological strategies brought into play by the unconscious mind to manipulate, deny, or distort reality in order to defend against feelings of anxiety and unacceptable impulses and to maintain one's self-schema or other schemas.
Ivor Montagu Ivor Goldsmid Samuel Montagu (23 April 1904, in Kensington, London – 5 November 1984, in Watford) was an English filmmaker, screenwriter, producer, film critic, writer, table tennis player, and Communist activist in the 1930s. He helped to develop a lively intellectual film culture in Britain during the interwar years, and was also the founder of the International Table Tennis Federation.
The Day the Music Died On February 3, 1959, American rock and roll musicians Buddy Holly, Ritchie Valens, and "The Big Bopper" J. P. Richardson were killed in a plane crash near Clear Lake, Iowa, together with pilot Roger Peterson. The event later became known as "The Day the Music Died" after singer-songwriter Don McLean referred to it as such in his 1971 song "American Pie".
Decree nisi A decree nisi or rule nisi (from Latin nisi 'unless') is a court order that will come into force at a future date unless a particular condition is met. Unless the condition is met, the ruling becomes a decree absolute (rule absolute), and is binding.
Botswana Botswana ( (listen), also UK: ), officially the Republic of Botswana (Setswana: Lefatshe la Botswana, [lɪˈfatsʰɪ la bʊˈtswana]), is a landlocked country in Southern Africa. Botswana is topographically flat, with up to 70 percent of its territory being the Kalahari Desert.
North American Free Trade Agreement The North American Free Trade Agreement (NAFTA ; Spanish: Tratado de Libre Comercio de América del Norte, TLCAN; French: Accord de libre-échange nord-américain, ALÉNA) was an agreement signed by Canada, Mexico, and the United States that created a trilateral trade bloc in North America. The agreement came into force on January 1, 1994, and superseded the 1988 Canada–United States Free Trade Agreement between the United States and Canada.
Regulation A In the United States under the Securities Act of 1933, any offer to sell securities must either be registered with the United States Securities and Exchange Commission (SEC) or meet certain qualifications to exempt it from such registration. Regulation A (or Reg A) contains rules providing exemptions from the registration requirements, allowing some companies to use equity crowdfunding to offer and sell their securities without having to register the securities with the SEC. Regulation A offerings are intended to make access to capital possible for small and medium-sized companies that could not otherwise bear the costs of a normal SEC registration and to allow nonaccredited investors to participate in the offering.
Formula One regulations The numerous Formula One regulations, made and enforced by the FIA and later the FISA, have changed dramatically since the first Formula One World Championship in 1950. This article covers the current state of F1 technical and sporting regulations, as well as the history of the technical regulations since 1950.
New York Codes, Rules and Regulations The New York Codes, Rules and Regulations (NYCRR) contains New York state rules and regulations. The NYCRR is officially compiled by the New York State Department of State's Division of Administrative Rules.
Risk Factors
FISHER SCIENTIFIC INTERNATIONAL INC Item 1A Risk Factors Our business is subject to a number of important risks and uncertainties
You should carefully consider the risk factors below as well as all the other information we have included in this Form 10-K 11 _________________________________________________________________ [66]Table of Contents Our growth strategy to acquire new businesses may not be successful and the integration of future acquisitions may be difficult and disruptive to our ongoing operations
Acquisitions are an important part of our growth strategy
Since 1991, we have acquired more than 40 businesses and we routinely review additional potential acquisition opportunities
Despite our successful record in integrating the companies we have acquired, certain risks exist, including the potential for: • management’s attention being diverted to the integration of the acquired businesses; • difficulties in integrating the operations and systems of the acquired businesses and in realizing operating synergies; and • difficulties in assimilating and retaining employees and customers of the acquired companies
None of these difficulties has historically been material, but if they were to be in the future, we may be unable to implement a portion of our growth strategy
In addition, we compete with other companies to acquire suitable acquisition targets and may not be able to acquire certain targets that we seek
Also, certain of the businesses we have acquired may not generate the cash flow and earnings or yield other benefits that we anticipated at the time of their acquisition
If we are unable to successfully complete and integrate strategic acquisitions in a timely manner, the acquisition may adversely affect our profitability
In addition, if we are unable to hire and retain key management personnel, we may not be able to execute our acquisition strategy
Our results of operations depend on our customers’ research and development efforts; these efforts and the spending on them are beyond our control, and our results of operations may be adversely affected if our customers do not continue expending sufficient resources on these activities
A significant number of our customers include entities active in scientific or technological research in the scientific research and clinical laboratory markets in the United States and internationally
Research and development budgets and activities have a large effect on the demand for our products and services
Our customers determine their research and development budgets based on several factors, including the need to develop new products, government funding, competition and the general availability of resources
In addition, as we continue to expand our international operations, the research and development spending levels in other markets will become increasingly important to us
Although we expect continued increases in scientific and technology-related research and development spending in the United States and worldwide, such spending may decrease or become subject to cyclical swings
Because we compete directly with certain of our largest customers and product suppliers, our results of operations could be adversely affected in the short term if these customers or suppliers abruptly discontinue or significantly modify their relationship with us
Our largest customer in the scientific products and services segment and our largest customer in the healthcare products and services segment are also significant competitors
Our business may be harmed in the short term if our competitive relationship in the marketplace with these customers results in a discontinuation of their purchases from us
In addition, we manufacture products that compete directly with products that we source from third-party suppliers
We also source competitive products from multiple suppliers
Our business could be adversely affected in the short term if any of our large third-party suppliers abruptly discontinues selling products to us
We may incur impairment charges on our goodwill and intangible assets with indefinite lives that would reduce our earnings
We are subject to Statement of Financial Accounting Standards (SFAS) Nodtta 142, “Goodwill and Other Intangible Assets,”(“SFAS 142”) which requires that goodwill and intangible assets that have an indefinite useful life be tested at least annually for impairment
Goodwill and other intangible assets with indefinite lives must also be tested for impairment between the annual tests if an event occurs, such as a downturn in our business or the loss of a significant customer, that would more likely than not reduce the fair value of the asset below its carrying amount
As of December 31, 2005, goodwill and other intangible assets with indefinite lives 12 _________________________________________________________________ [67]Table of Contents represented approximately 57prca of our total assets
If we determine that there has been an impairment, our financial results for the relevant period will be reduced by the amount of the impairment, net of income tax effects, if any
We rely heavily on manufacturing operations to produce the products we sell, and our business could be adversely affected by disruptions of our manufacturing operations
We rely upon our manufacturing operations to produce many of the products we sell
Any significant disruption of those operations for any reason, such as strikes or other labor unrest, power interruptions, fire, or other events beyond our control could adversely affect our sales and customer relationships and therefore adversely affect our business
Although most of our raw materials are available from a number of potential suppliers, our operations also depend upon our ability to obtain raw materials at reasonable prices
If we are unable to obtain the materials we need at a reasonable price, we may not be able to produce certain of our products or we may not be able to produce certain of these products at a marketable price, which could have an adverse effect on our results of operations
We have implemented, and will continue to implement, various cost-savings initiatives that may not achieve the anticipated results
We have implemented and approved a number of programs designed to reduce costs
We also expect that we will continue to identify opportunities for operational efficiencies and implement programs designed to achieve these efficiencies
Such programs will require, among other things, the consolidation and integration of facilities, functions, systems, and procedures, all of which present significant management challenges
There can be no assurance that such actions will be accomplished as rapidly as anticipated or that the full extent of expected cost reductions will be achieved
During 2005, most of our cost savings initiatives related to the integration of Apogent businesses
The integration of Apogent and the associated cost savings programs proceeded as planned during 2005
Our indebtedness could adversely affect our financial health and prevent us from fulfilling our financial obligations
As of December 31, 2005, we had total indebtedness of dlra2cmam210dtta1 million
In addition, as of December 31, 2005, we had the ability to incur an additional aggregate amount of dlra988dtta5 million of indebtedness under our existing accounts receivable securitization facility and revolving credit facility
Further borrowing under those facilities or incurring any other additional indebtedness would increase our leverage and our risks
Our debt agreements permit us to incur or guarantee additional indebtedness, subject to limitations set forth in those agreements
Our indebtedness could negatively affect our operations in a number of ways including: • increasing our vulnerability to generally adverse economic and industry conditions; • reducing the availability of our cash flows to fund working capital, capital expenditures, research and development efforts, program investment efforts and other general corporate needs; • limiting our flexibility in planning for, or reacting to, changes in our business and the industry in which we operate; • exposing us to the risk of increased interest rates because some of our debt has variable interest rates; and • limiting our ability to borrow additional funds
Any default under the agreements governing our credit facility or our other outstanding indebtedness and the remedies sought by the holders of such indebtedness could make us unable to pay principal and interest on our outstanding indebtedness
13 _________________________________________________________________ [68]Table of Contents In addition, we will be required to repay the indebtedness under our various debt agreements as that indebtedness matures
We may not have sufficient funds or we may be unable to arrange for additional financing to pay these amounts when they become due
” Because we rely heavily on third-party package-delivery services, a significant disruption in these services or significant increases in prices may disrupt our ability to ship products, increase our costs and lower our profitability
We ship a significant portion of our products to our customers through independent package delivery companies, such as UPS and Federal Express in the US and DHL in Europe
We also maintain a small fleet of vehicles dedicated to the delivery of our products and ship our products through other carriers, including national and regional trucking firms, overnight carrier services and the US Postal Service
If UPS or another third-party package-delivery provider experiences a major work stoppage (as UPS did in 1997), preventing our products from being delivered in a timely fashion or causing us to incur additional shipping costs we could not pass on to our customers, our costs could increase and our relationships with certain of our customers could be adversely affected
In addition, if UPS or our other third-party package-delivery providers increase prices, and we are not able to find comparable alternatives or make adjustments in our delivery network, our profitability could be adversely affected
We are subject to regulation by various federal, state and foreign agencies that require us to comply with a wide variety of regulations, including those regarding the manufacture of products, the shipping of our products and environmental matters
Some of our operations are subject to regulation by the US Food and Drug Administration and similar international agencies
These regulations govern a wide variety of product activities, from design and development to labeling, manufacturing, promotion, sales and distribution
If we fail to comply with the US Food and Drug Administration’s regulations or those of similar international agencies, we may have to recall products and cease their manufacture and distribution, which would increase our costs and reduce our revenues
We are subject to federal, state, local and international laws and regulations that govern the handling, transportation, manufacture, use or sale of substances that are or could be classified as toxic or hazardous substances
Some risk of environmental damage is inherent in our operations and the products we manufacture, sell or distribute
This requires us to devote significant resources to maintain compliance with applicable environmental laws and regulations, including the establishment of reserves to address potential environmental costs, and manage environmental risks
If we lose our key personnel, our business could be adversely affected
We depend heavily on the services of our senior management, including Paul M Montrone, our Chairman of the Board and Chief Executive Officer, and Paul M Meister, our Vice Chairman of the Board, both of whom are important to our acquisition and earnings-growth strategy
We believe our future success will depend upon the continued services of our senior management
Our business could be adversely affected by the loss of any member of our senior management, including Mr
Montrone or Mr
We do not maintain key-man life insurance in respect of Mr
We are subject to economic, political and other risks associated with our significant international sales and operations, which could adversely affect our business
We conduct international operations through a variety of wholly owned subsidiaries, majority-owned subsidiaries, joint ventures, equity investments and agents located in North and South America, Europe, the Far East, the Middle East and Africa
A significant portion of the revenues of our international operations is generated in Europe
Expansion of these activities could increase the risks associated with our international operations
Sales outside the United States were approximately 25prca and 24prca of total sales in 2005 and 2004, 14 _________________________________________________________________ [69]Table of Contents respectively
We anticipate that sales from international operations will continue to represent a growing portion of our revenues
In addition, many of our manufacturing facilities, employees and suppliers are located outside the United States
Our sales and earnings could be adversely affected by a variety of factors resulting from our international operations, including: • changes in the political or economic conditions in a country or region, particularly in developing or emerging markets; • future fluctuations in exchange rates; • trade-protection measures and import-or export-licensing requirements; • differing tax laws and changes in those laws; • difficulty in staffing and managing widespread operations; and • differing regulatory requirements and changes in those requirements
We may be unable to adjust to rapid changes in the healthcare industry, some of which could adversely affect our business
The healthcare industry has undergone significant changes in an effort to reduce costs
These changes include: • development of large and sophisticated groups purchasing medical and surgical supplies; • wider implementation of managed care; • legislative healthcare reform; • consolidation of pharmaceutical companies; • increased outsourcing of certain activities, including to low-cost offshore locations; and • consolidation of distributors of pharmaceutical, medical and surgical supplies
We expect the healthcare industry to continue to change significantly in the future
Some of these potential changes, such as a reduction in governmental support of healthcare services or adverse changes in legislation or regulations governing the delivery or pricing of healthcare services or mandated benefits, may cause healthcare-industry participants to purchase fewer of our products and services or to reduce the prices they are willing to pay for our products or services
We may incur unexpected costs from increases in fuel and raw material prices, which could reduce our earnings and cash flow
During 2005, we experienced price increases in fuel and raw materials, including petroleum-based resins
We were able to minimize the impact of these price increases through higher prices to customers and various cost-saving measures
While we will continue to implement such initiatives to minimize the impact of future price increases, our earnings and cash flows could be adversely affected in the event these measures were insufficient to cover our costs
For further discussion regarding our commodity risks refer to “Item 7A — Quantitative and Qualitative Disclosures About Market Risk — Commodity Risk Management
” If we experience a significant disruption in our information technology systems or if we fail to implement new systems and software successfully, our business could be adversely affected
We depend on the information systems throughout our Company to manufacture products, process orders, manage inventory, process shipments to customers and respond to customer inquiries
If we were to experience a prolonged disruption in the information technology systems that involve our interactions with 15 _________________________________________________________________ [70]Table of Contents customers and suppliers, it could result in the loss of sales and customers, which could adversely affect our business
Exchange rate fluctuations may adversely affect our business
Since we are a multinational corporation that sells products and sources products in many different countries, changes in exchange rates could adversely affect our cash flows and results of operations
Our businesses occasionally invoice third-party customers or are invoiced for product purchases in currencies other than the one in which they primarily do business (the “functional currency”)
Movements in the invoiced currency relative to the functional currency result in foreign currency transaction gains and losses, which could adversely affect our cash flows and our results of operations
Furthermore, reported sales and purchases made in non-US currencies by our international businesses, when translated into US dollars for financial reporting purposes, fluctuate due to exchange rate movement
Due to the number of currencies involved, the variability of currency exposures and the potential volatility of currency exchange rates, we cannot predict the effects of exchange-rate fluctuations upon future operating results
For further discussion regarding our currency risks refer to “Item 7A — Quantitative and Qualitative Disclosures About Market Risk — Currency Risk Management